Mathew Knowles is a record label owner, talent manager, and businessman. He is best known for being the manager of Destiny's Child. He also managed his daughters Beyoncé and Solange Knowles. He is the ex-husband of Tina Knowles, and father-in-law of Jay-Z.

Knowles began his business career in sales of office and medical equipment. He moved to Houston in 1976 and worked for the Xerox Corporation for 10 years, primarily in the medical-systems sales division. Knowles afterward worked selling a CT/MRI diagnostic imaging equipment to hospitals and health facilities. He also worked in neurosurgical sales. In 1992, Knowles left this career to devote himself to his music company, Music World Entertainment, which he founded that year.

Knowles established several recording imprints under Music World Entertainment, including Music World Gospel, Music World Kids, and Music World Country/Compadre. Knowles also established joint ventures with Sony Music, Interscope/Geffen/A&M, Fontana/Universal, Integrity Africa, Fontana International, and Sony Brazil.

In 2002 Knowles founded Spirit Rising Music, which became Music World Gospel. Its artists include Vanessa Bell Armstrong, Brian Courtney Wilson, Micah Stampley, Juanita Bynum, Le'Andria Johnson, Amber Bullock, Andrea Helms, Trinitee 5:7, and Elder Goldwire. In 2016, through Music World Music, Knowles acquired the country music catalog Compadre, which includes Johnny Cash, Billy Joe Shaver, James McMurty, Trent Willmon, and Kate Campbell. Knowles also launched the family-oriented music imprint, Music World Kids. The label has released youth projects that include Baby Jamz, Krazy Kuzins, Kid's Rap Radio, and the Music World Kids CD 5-pack. The venture also has released music from Nickelodeon's popular cartoon series, Wow! Wow! Wubbzy!.

Knowles became manager of the vocal group Destiny's Child, working as either a producer or an executive producer on many of the group's projects. Under Music World Artist Management, Destiny's Child became a top-selling group, winning several awards include the Grammy Award, the American Music Award, BET Awards, and many others. Billboard magazine inducted the group into the All Time Hot 100 Artists. Following the departure of his daughter Beyoncé from the group, Knowles managed the solo careers of the other members of Destiny's Child, Michelle Williams and Kelly Rowland.

In addition to his work in music, Knowles is also one of the executive producers of the 2009 movie Obsessed, which stars Beyoncé. He is also executive producer of, and is featured in, two reality series: The UK's Chancers, and MTV International's Breaking From Above.

In October 2015, Mathew Knowles released his first book, "The DNA Of Achievers: 10 Traits of Highly Successful Professionals". In an interview with Madamenoire.com, he spoke about teaching entrepreneurship on the college level, and his entertainment industry seminars.

In March 2018, Billboard announced that Mathew Knowles joined the advisory board of Tunedly, an online recording studio for songwriters.

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